Subcellular location of PKCalphaII-GFP (green) in Green Monkey COS-7 cells using laser scanning confocal microscopy two days after transfection. The actin cytoskeleton is stained with Texas Red-phalloidin and the endoplasmic reticulum (purple) identified with an antibody to calreticulin.   By Lorene Langeberg, Scott Lab Manager at the Howard Hughes Medical Institute, Portland, OR.
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Biochemistry Across the School Curriculum

BASC 10 - Genetic Basis of Disease

This booklet looks at how genetic disorders may arise including single-gene disorders, chromosomal and mitochondrial disorders. It also looks at how the knowledge of these disorders may help in the treatment and management of affected individuals.

The booklet can be downloaded in full or in sections using the links below.

Articles are available in Adobe PDF format and you will require Acrobat reader to view, which is available to download for free.


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